Serum cardiac troponin i and lactate as prognostic markers of Canine African Trypanosomiasis

The study was aimed at understanding the nature and pattern of serum lactate, cardiac troponin I changes associated with acute Trypanosoma brucei infection dogs. It also seeks to investigate usefulness these biomarkers in monitoring disease progression predicting mortality. Twenty healthy adult dogs both sexes were used for study. All intra-peritoneally inoculated 1ml phosphate buffered saline diluted blood containing 1x106 Lafenwa strain T. brucei. I, potassium, sodium, chloride bicarbonate monitored before 16 24 days after infection. There a progressive increase values potassium various A significant association found between lactate heart rate, I. This result has shown that there could be myocardial damage due hypoxia anemia hypo-perfusion canine African trypanosomiasis. help severity outcome Canine Trypanosomiasis. Lactic acidosis may ventilation drive consequently rates infected